The truck is propelled by a 5.6L VK56DE V8 engine (315hp [227kW] @ 4,900 rpm and 390lb·ft (529N·m) torque @ 3,600 rpm) and a 5-speed automatic transmission with an overdrive. Each cylinder in the engine is lined with cast iron. The valvetrain is a DOHC design with four valves per cylinder. Infiniti designed the QX56's throttle responsiveness to correspond to specific drivetrain modes: when the driver selects all-wheel drive, the throttle becomes less sensitive, presumably to allow easier regulation of acceleration when off-road.
The Infiniti QX56 has around 9,000 lb (4082 kg) of towing capacity. Mileage at peak performance drain is 12miles per US gallon (20L/100km; 14mpg-imp). It comes in one trim level, with only key options such as: DVD entertainment system, 4WD/2WD, and a bench instead of captain chairs as the second row. Other features which come standard are a ten-speaker Bose system, DVD-based navigation system, leather trim for all seats, dual-climate control, 18-inch chrome alloy wheels, and an adaptive cruise control system. A precrash system is a novelty in the market as well.